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  • Title: [Study on preparation of the inclusion compound of curcumin with beta-cyclodextrin].
    Author: Han G, Xu J, Li W, Ning C.
    Journal: Zhong Yao Cai; 2004 Dec; 27(12):946-8. PubMed ID: 15807250.
    Abstract:
    OBJECTIVE: The inclusion compound of curcumin with, beta-CD was preparated to increase the solubility and bioavaliability of curcumin. METHODS: Prepare inclusion compound was studied with orthogonal design. The inclusion compound was verified with fluorometry, TLC, and phase solubility. RESULT: The best way to prepare inclusion compound are as follows: the molar ratio between curcumin and, beta-CD is 1:1, temperture is 40 degrees C, reaction time is 2 h. CONCLUSION: Solubility of inclusion compound is 10 times than curcumin.
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