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  • Title: A retrospective series of long-term survivors of metastatic breast cancer in complete remission.
    Author: Amoroso V, Valcamonico F, Simoncini E, Ardighieri L, Grisanti S, Vassalli L, Marpicati P, Lucini L, Ferrari VD, Rangoni G, Marini G.
    Journal: Oncology; 2005; 68(1):48-51. PubMed ID: 15809519.
    Abstract:
    AIM: To describe clinical features, treatment modalities and long-term outcome of patients with overt metastatic breast cancer in complete remission for more than 5 years. PATIENTS AND METHODS: A retrospective survey of 12 patients who were referred to a single institution from 1982 to 1995. RESULTS: The majority of the long-term survivors had a good performance status, endocrine-responsive disease and a single metastatic site. Ten patients had received chemotherapy, 8 patients hormone therapy, and 2 patients had been treated with surgery followed by systemic therapies. At a median follow-up of 11.7 years, 10 of the 12 patients were still in complete remission. The median duration of complete remission was 9.2 years (range 5.0-15.7 years). CONCLUSIONS: This case series confirms that only a few metastatic breast cancer patients could potentially be cured with multidisciplinary treatments.
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