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  • Title: [Evaluation after 20 years of a case of Takayasu's disease that presented with aortic regurgitation].
    Author: Pierre B, Machet MC, Marchand M, Alison D, Casset-Senon D, Fauchier L, Charniot JC, Babuty D, Cosnay P.
    Journal: Arch Mal Coeur Vaiss; 2005 Mar; 98(3):255-8. PubMed ID: 15816330.
    Abstract:
    Takayasu's disease is a segmental multifocal affection of medium and large arteries. The diagnosis is based on the association of stenotic and aneurismal lesions of the aorta and its branches secondary to an inflammatory infiltration of the media and adventitia. Cases of aortic regurgitation associated with aneurismal dilatation of the ascending aorta as the presenting features of Takayasu's disease, as in this case, are rare. Histological examination of the aortic wall may help establish the diagnosis by showing signs of aortitis. The other usual arterial lesions are sometimes missing at the initial phase of the disease. A late histological diagnosis may be difficult as the inflammatory lesions tend to be progressively replaced by fibrotic lesions or a banal atheroma.
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