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  • Title: A novel formal total synthesis of cephalotaxine.
    Author: Li WD, Ma BC.
    Journal: J Org Chem; 2005 Apr 15; 70(8):3277-80. PubMed ID: 15822994.
    Abstract:
    A formal total synthesis of cephalotaxine (CET), the parent structure of antileukemia Cephalotaxus alkaloids, was achieved through a novel synthesis of the pentacyclic amino enone 4 by a rapid annulation of readily available beta-(3,4-methylenedioxy)phenethylamine (2), delta-valerolactone, and bromoacetone.
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