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  • Title: Cardiac resynchronization therapy: retiming the failing right ventricle.
    Author: Cowburn PJ, Parker JD, Cameron DA, Harris L.
    Journal: J Cardiovasc Electrophysiol; 2005 Apr; 16(4):439-43. PubMed ID: 15828891.
    Abstract:
    Cardiac resynchronization therapy (CRT) improves symptoms, reduces hospitalization, and may decrease mortality in patients with moderate/severe heart failure and left bundle branch block. Whether CRT may have a role in the management of patients with adult congenital heart disease and a failing right (systemic) ventricle is unknown. We report the case of an adult patient with transposition of the great arteries and previous Mustard's repair, who successfully underwent CRT using a hybrid transvenous/epicardial approach. Exercise tolerance improved, right ventricular (systemic) ejection fraction improved, diuretic requirements reduced, and renal function improved. CRT may offer a new therapeutic option for this patient population.
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