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  • Title: [The effect of the physiological state of Escherichia coli on the nucleoid ultrastructure under stress exposures].
    Author: Tkachenko AG, Chudinov AA, Churilova NS.
    Journal: Izv Akad Nauk SSSR Biol; 1992; (1):42-51. PubMed ID: 1583209.
    Abstract:
    The energetic state and activity of polyamine-synthesizing system of E. coli were studied under conditions of aerobic-anaerobic and pH transitions, nutrition shifts, osmotic and heat shocks. The electron microscopy of cells showed a correlation between cell physiological state and nucleoid ultrastructure. The role of energetic status and polyamines in the regulation of DNA supercoiling is discussed which is a putative cause for the changes observed in the nucleoid ultrastructure.
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