These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Mucosal vaccination with an attenuated maedi-visna virus clone.
    Author: Pétursson G, Matthíasdóttir S, Svansson V, Andrésdóttir V, Georgsson G, Martin AH, Agnarsdóttir G, Gísladóttir E, Arnadóttir S, Högnadóttir S, Jónsson SR, Andrésson OS, Torsteinsdóttir S.
    Journal: Vaccine; 2005 May 02; 23(24):3223-8. PubMed ID: 15837223.
    Abstract:
    Four sheep were infected intratracheally with an attenuated molecular clone of maedi-visna virus (MVV). All four became infected. Ten months later these sheep were challenged intratracheally with a genetically similar but pathogenic clone of MVV. Four unvaccinated sheep were infected simultaneously. All sheep became infected by the challenge virus. The vaccinated sheep were not protected against superinfection with the challenge clone. However, virus was isolated more frequently from the blood of the unvaccinated controls than of the vaccinated animals and ten times more frequently from lungs of unvaccinated sheep than from lungs of vaccinated sheep at sacrifice, indicating partial protection.
    [Abstract] [Full Text] [Related] [New Search]