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  • Title: Effect of chronic total coronary occlusion on treatment strategy.
    Author: Christofferson RD, Lehmann KG, Martin GV, Every N, Caldwell JH, Kapadia SR.
    Journal: Am J Cardiol; 2005 May 01; 95(9):1088-91. PubMed ID: 15842978.
    Abstract:
    In a registry analysis of 8,004 consecutive patients presenting for diagnostic catheterization at a single institution from 1990 to 2000, chronic total occlusion (CTO) was found in 52% of patients with significant (> or = 70% diameter stenosis) coronary artery disease. Peripheral vascular disease was the strongest clinical predictor of the presence of a CTO. In a multivariate analysis, CTO was the strongest predictor against the selection of percutaneous coronary intervention (PCI) as a treatment strategy, indicating that efforts to improve the success rate of PCI in CTO may have a significant impact on management of coronary disease.
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