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  • Title: Methylprednisolone pulse therapy for massive lymphadenopathy in a child with intravenous immunoglobulin-resistant Kawasaki disease.
    Author: Chen HH, Liu PM, Bong CN, Wu YT, Yang KD, Wang CL.
    Journal: J Microbiol Immunol Infect; 2005 Apr; 38(2):149-52. PubMed ID: 15843862.
    Abstract:
    Kawasaki disease (KD) is an acute febrile multi-system vasculitis of unknown etiology. The diagnosis is based on clinical features. We describe a case of intravenous immunoglobulins (IVIG)-resistant KD presenting with persistent fever and massive cervical lymphadenopathy associated with mild respiratory distress. The symptoms resolved after methylprednisolone pulse therapy. High-dose pulse steroid may be an alternative therapeutic option in KD which presents with possible life-threatening complications or failure to respond to high-dose IVIG infusion.
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