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  • Title: Adenylate cyclase and ATPase activities in red cell membranes of patients and genetic carriers of Duchenne muscular dystrophy.
    Author: Wacholtz MC, Raible DG, Jackowski S, Rodan SB, Rodan GA, Sha'afi RI.
    Journal: Clin Chim Acta; 1979 Sep 03; 96(3):255-9. PubMed ID: 158446.
    Abstract:
    Basal adenylate cyclase activity was increased in red cell ghosts from both patients with Duchenne muscular dystrophy and their mothers when the activities were compared to proper age-matched controls. The activity of ATPase measured in the presence of Na+, K+, and Mg2+ was not found to be different in erythrocyte ghosts from Duchenne dystrophic patients, age-matched controls, or the mothers of Duchenne patients, and ouabain inhibited ATPase in ghosts to the same extent in all membrane preparations.
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