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  • Title: Role of zoledronic acid in the setting of bone metastases from non-small-cell lung cancer.
    Author: Langer CJ.
    Journal: Clin Lung Cancer; 2005 Mar; 6(5):314-6. PubMed ID: 15845184.
    Abstract:
    Bone metastases are major sequelae of non-small-cell lung cancer and are associated with poor survival, skeletal-related events (SREs), and economic burden. In recent phase III trials, zoledronic acid has demonstrated a potential to prevent or delay SREs, although this has not yet translated into a survival benefit. Zoledronic acid is the first and only bisphosphonate with proven efficacy in the treatment of bone metastases associated with a broad range of tumors, including lung cancer. We report herein a case study that highlights the clinical benefit of zoledronic acid in a patient with squamous cell carcinoma of the lung.
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