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  • Title: Analysis of local recurrence of midrectal cancer after low anterior resection and stapled anastomosis.
    Author: Fuhrman GM, Davidson BS, Larach SW, Williamson PR.
    Journal: South Med J; 1992 May; 85(5):502-5. PubMed ID: 1585203.
    Abstract:
    We evaluated local recurrences of midrectal cancer in 33 patients treated with low anterior resection and stapled end-to-end anastomosis. All patients had follow-up for at least 2 years or until death. There were 21 men and 12 women. Data were analyzed with attention to Astler-Coller modified Dukes' stage, distal margin of resection, degree of histologic differentiation, location of the tumor, blood transfusion, and adjuvant therapy. Distal margin of resection, histologic differentiation, and location of the tumor had no prognostic significance regarding local recurrence. The use of adjuvant therapy remains controversial. The immunosuppressive effects of blood transfusion may affect local recurrence. Dukes' staging remains the standard for prognosis of recurrence in rectal cancer.
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