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  • Title: Prevalence and characterization of invasive isolates of Streptococcus pyogenes with reduced susceptibility to fluoroquinolones.
    Author: Powis J, McGeer A, Duncan C, Goren R, de Azavedo JC, Bast DJ, Pong-Porter S, Mazzulli T, Green K, Willey B, Low DE.
    Journal: Antimicrob Agents Chemother; 2005 May; 49(5):2130-2. PubMed ID: 15855546.
    Abstract:
    Fluoroquinolone susceptibility testing was performed on invasive group A streptococcus isolates from 1992-1993 and 2003 from Ontario, Canada. None were nonsusceptible to levofloxacin. Two of 153 (1.3%) from 1992-1993 and 7 of 160 (4.4%) from 2003 had a levofloxacin MIC of 2 mug/ml; all nine had parC mutations, and eight were serotype M6.
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