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  • Title: Thrombophilia and venous thromboembolism. International consensus statement. Guidelines according to scientific evidence.
    Author: European Genetics Foundation, Cardiovascular Disease Educational and Research Trust, International Union of Angiology, Mediterranean League on Thromboembolism, Nicolaides AN, Breddin HK, Carpenter P, Coccheri S, Conard J, De Stefano V, Elkoofy N, Gerotziafas G, Guermazi S, Haas S, Hull R, kalodiki E, Kristof V, Michiels JJ, Myers K, Pineo G, Prandoni P, Romeo G, Samama MM, Simonian S, Xenophonthos S.
    Journal: Int Angiol; 2005 Mar; 24(1):1-26. PubMed ID: 15876995.
    Abstract:
    Thrombophilia is the term now used to describe predisposition to increased risk of venous and occasionally arterial thromboembolism due to hematological abnormalities. It can be a multifactorial disorder where congenital defects of anticoagulant or procoagulant factors may be combined with acquired hematological abnormalities. It should be considered in patients with a documented unexplained thrombotic episode or a positive family history. The aim of this document is to provide guidelines for investigation and management of patients with thrombophilia in the presence or absence of venous thromboembolism (VTE).
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