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  • Title: [Regulatory-adaptive abilities of hypertensive patients treated with lisinopril and atenolol].
    Journal: Ter Arkh; 2005; 77(3):69-71. PubMed ID: 15881105.
    Abstract:
    AIM: To examine regulatory-adaptive possibilities of hypertensive patients treated with lisinopril and atenolol. MATERIAL AND METHODS: Monotherapies with lisinopril and atenolol were compared in relation to effect on arterial pressure and parameters of cardiac-respiratory synchronism after a single and 5-week intake in 37 patients. RESULTS: Lisinopril increased in 19 patients the range of synchronization by 28.5% (p < 0.05) after a single dose and by 40% (p < 0.001) after 5-week treatment. Atenolol had an adequate hypotensive effect in 18 patients but promoted a decrease of range sychnonization by 41% (p < 0.00001) after a single intake. CONCLUSION: Hypotensive drugs should be studied for effects on regulatory-adaptive ability of the organism.
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