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  • Title: FcgammaRIIIb and complement component C7 codeficiency in a patient with recurrence of fulminant meningococcal septic shock.
    Author: Debard AL, Lamy B, Monneret G, Mira JP, Pachot A, Kleijer M, Aillaud MF, Boibieux A, Bienvenu J, Carret G, Fournier G, Bohé J.
    Journal: Clin Infect Dis; 2005 Jun 01; 40(11):1679-83. PubMed ID: 15889368.
    Abstract:
    Individuals with deficiencies of the late components of complement exhibit a susceptibility to the recurrence of meningococcal disease with a usually mild clinical presentation. We report the recurrence of fulminant meningococcal disease in a complement component C7-deficient patient. We found a total deficiency of FcgammaRIIIb on neutrophils, which could partially explain the unusually severe clinical presentation.
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