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  • Title: Reduced word-repetition effect in the event-related potentials of thought-disordered patients with schizophrenia.
    Author: Matsumoto K, Yamazaki H, Nakamura M, Sakai H, Miura N, Kato T, Miwa S, Ueno T, Saito H, Matsuoka H.
    Journal: Psychiatry Res; 2005 Apr 30; 134(3):225-31. PubMed ID: 15892981.
    Abstract:
    Repetition effect in event-related potentials (ERPs) was studied in 10 non-thought-disordered (non-TD) patients with schizophrenia, 8 thought-disordered (TD) patients with schizophrenia, and 10 normal control subjects while they performed a semantic categorization task with incidental word repetitions. All patients were in a stable or partially remitted stage. Although both healthy control and non-TD groups produced more positive ERPs to the repeated words than to the new words (ERP repetition effect) for 250-500 ms, the TD group did not show the ERP repetition effect. These findings suggest that the abnormal attenuation of the ERP repetition effect during semantic processing may be more prominent in schizophrenic patients with thought disorder than in those without the symptom.
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