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  • Title: Virus-associated hemophagocytic syndrome in an international traveler as a differential diagnosis of SARS.
    Author: Ishii H, Asai S, Suzuki T, Eguchi K, Miyachi H.
    Journal: Intern Med; 2005 Apr; 44(4):342-5. PubMed ID: 15897649.
    Abstract:
    During the epidemic of severe acute respiratory syndrome in 2003, a 27-year- old Japanese woman presented a high fever and acute respiratory distress with pulmonary infiltrates after traveling to a high-risk area. An alternative diagnosis was made as Epstein-Barr virus-associated hemophagocytic syndrome, based on the proliferation of macrophages with hemophagocytosis in the bone marrow and Epstein-Barr viral marker profiles. Virus-associated hemophagocytic syndrome in an international traveler should be included in the differential diagnosis of severe acute respiratory syndrome.
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