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  • Title: Biosynthesis of conjugatable saccharidic moieties of GM2 and GM3 gangliosides by engineered E. coli.
    Author: Fort S, Birikaki L, Dubois MP, Antoine T, Samain E, Driguez H.
    Journal: Chem Commun (Camb); 2005 May 28; (20):2558-60. PubMed ID: 15900325.
    Abstract:
    Oligosaccharidic moieties of GM(2) and GM(3) gangliosides bearing an allyl or a propargyl aglycon, are efficiently biosynthesized on the gram scale by growing metabolically engineered Escherichia coli cells in the presence of the corresponding lactoside acceptors and sialic acid.
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