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Title: Overview of biologic agents in medicine and dermatology. Author: Sobell JM. Journal: Semin Cutan Med Surg; 2005 Mar; 24(1):2-9. PubMed ID: 15900793. Abstract: Three agents have recently been approved by the Food and Drug Administration for the treatment of chronic plaque psoriasis: alefacept, efalizumab, and etanercept. The field of dermatology has now entered a new era, joining other disciplines of medicine that have been using biologic agents for decades. These new therapies offer psoriatic patients the potential for safe and effective long-term management of this disease. This article reviews how an increased understanding of the pathophysiology of psoriasis led to the development of these products.[Abstract] [Full Text] [Related] [New Search]