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Title: Synthesis of the C12-C19 fragment of (+)-peloruside A through a diastereomer-discriminating RCM reaction. Author: Roulland E, Ermolenko MS. Journal: Org Lett; 2005 May 26; 7(11):2225-8. PubMed ID: 15901175. Abstract: [reaction: see text]. A short and efficient asymmetric synthesis of the C12-C19 fragment of the cytotoxic macrolide (+)-peloruside A has been achieved via a highly diastereomer-discriminating RCM of alpha-branched but-3-enoate ester of a methallylic alcohol derived from hydrolytically resolved (S)-(-)-propylene oxide.[Abstract] [Full Text] [Related] [New Search]