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  • Title: Alginate lyase (AlgL) activity is required for alginate biosynthesis in Pseudomonas aeruginosa.
    Author: Albrecht MT, Schiller NL.
    Journal: J Bacteriol; 2005 Jun; 187(11):3869-72. PubMed ID: 15901714.
    Abstract:
    To determine whether AlgL's lyase activity is required for alginate production in Pseudomonas aeruginosa, an algLdelta::Gm(r) mutant (FRD-MA7) was created. algL complementation of FRD-MA7 restored alginate production, but algL constructs containing mutations inactivating lyase activity did not, demonstrating that the enzymatic activity of AlgL is required for alginate production.
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