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  • Title: [Structural changes in the rat myocardium in the process of adaptation to high-altitude hypoxia].
    Author: Kononova VA.
    Journal: Biull Eksp Biol Med; 1979 Oct; 88(10):497-500. PubMed ID: 159083.
    Abstract:
    Changes in the weight of diverse parts of the heart, in cross-sectional area of myocytes and vascularization of the myocardium were studied in rat experiments under altitude hypoxia (3200 m above the sea level) during adaptation of the animals to hypoxia. Morphologically, the compensatory and adaptive reactions of the rat to hypoxia were shown by its increases weight at the expense of hypertrophy of the right ventricular myocardium. Vascularization of the myocardium augmented synchronously to its growing hypertrophy.
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