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  • Title: [Effect of long-term phenytoin treatment on the levels of calcium and magnesium in rat femurs].
    Author: Maurat JP, Bugnon C, Rousselet F, Fellmann D, Becque O, Techenet P.
    Journal: C R Seances Soc Biol Fil; 1978; 172(6):1114-8. PubMed ID: 159098.
    Abstract:
    In young male rats, long-term treatment with phenytoïn reduces the amount of calcium and magnesium in the femurs and provokes a stimulation of the parathyroiïds witnessed by the hypertrophy and hyperplasy of the parathyroid cells. Neither plasma calcium nor plasma and erythrocyte magnesium are modified.
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