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  • Title: [Salmonella of Indian origin: pseudo-susceptibility to fluoroquinolones].
    Author: Denes E, Gondran G, Bezanahary H, Genet C, Rogez JP, Weinbreck P, Martin C.
    Journal: Med Mal Infect; 2005 Apr; 35(4):223-4. PubMed ID: 15914292.
    Abstract:
    We report the case of a patient presenting with typhoid fever after returning from a stay in India. This infection was not cured with a course of ciprofloxacin, due to a reduced susceptibility of the bacteria to the drug. This decreased susceptibility to fluoroquinolones was not detected by the antibiogram, but the MIC for nalidixic acid was greater than 32 mg/l. This case suggests using a third generation cephalosporin instead of a quinolone, for people coming from a high-risk zone. It also suggests that the MIC for nalidixic acid and for norfloxacin can be used as the first clue for a reduced susceptibility to fluoroquinolones.
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