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  • Title: Bacterial isolation and antimicrobial susceptibilities in patients with infective endocarditis.
    Author: Srifuengfung S, Yungyuen T, Komolpis P.
    Journal: Southeast Asian J Trop Med Public Health; 2004 Dec; 35(4):897-901. PubMed ID: 15916088.
    Abstract:
    Infective endocarditis is life-threatening and urgent treatment is needed. We review here 6217 patients with infective endocarditis admitted to Siriraj Hospital during a 20 year period, 1982-2001. In this retrospective study, we obtained our data from hemoculture results. Bacterial pathogens were found in only 834 patients (13.41%). Of the five most common pathogens, nonfermentative gram-negative rods (N.F.) ranked first (20.94%), followed by coagulase-negative staphylococci (12.47%), viridans streptococci (10.23%), Staphylococcus aureus (9.29%), and Escherichia coli (8.59%). Of the N.F., the sensitivities were: cefoperazone/sulbactam (86%), piperacillin/tazobactam (86%), meropenem (84%), imipenem (83%), ceftazidime (78%), ofloxacin (85%), ciprofloxacin (71%), and co-trimoxazole (71%).
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