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  • Title: In vitro activity of telithromycin against macrolide-susceptible and macrolide-resistant pharyngeal isolates of group A streptococci in the United States.
    Author: Green M, Allen C, Bradley J, Dashefsky B, Gilsdorf JR, Marcon MJ, Schutze GE, Smith C, Walter E, Martin JM, Edwards KA, Barbadora KA, Rumbaugh RM, Wald ER.
    Journal: Antimicrob Agents Chemother; 2005 Jun; 49(6):2487-9. PubMed ID: 15917551.
    Abstract:
    In vitro susceptibility testing of 2,797 group A streptococcus (GAS) isolates demonstrated that telithromycin was fully active against all macrolide-susceptible strains and among 80 of 115 macrolide-resistant GAS expressing the M phenotype. Telithromycin resistance was identified in 2 of 45 strains expressing the inducible macrolide-lincosamide-streptogramin B phenotype and four of nine isolates expressing the constitutive macrolide-lincosamide-streptogramin B resistance phenotype.
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