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  • Title: Familial bilateral acinic cell carcinoma of the parotid synchronous with pituitary adenoma: case report.
    Author: Delides A, Velegrakis G, Kontogeorgos G, Karagianni E, Nakas D, Helidonis E.
    Journal: Head Neck; 2005 Sep; 27(9):825-8. PubMed ID: 15920750.
    Abstract:
    BACKGROUND: Acinic cell carcinoma is a common neoplasm of the salivary glands that occurs predominately in the parotid. Only one case of a familial recurrence of such a neoplasm and 16 cases of bilateral tumors have been reported. METHODS: History files and histologic reports of a patient with bilateral multifocal acinic cell carcinoma of the parotid and a synchronous pituitary adenoma, and of the patient's sister and his father, also treated for parotid tumours, were retrieved. RESULTS: There was one recurrence of acinic cell carcinoma in the family. A pituitary tumor was a chromophobe gonotrophic adenoma. CONCLUSIONS: This is the 17th case of bilateral acinic cell carcinoma of the parotid gland and the second reported case with a familial recurrence. It is the first with a synchronous pituitary adenoma.
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