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  • Title: Synthesis of substituted indole derivatives as a new class of antimalarial agents.
    Author: Agarwal A, Srivastava K, Puri SK, Chauhan PM.
    Journal: Bioorg Med Chem Lett; 2005 Jun 15; 15(12):3133-6. PubMed ID: 15925306.
    Abstract:
    A series of substituted indole derivatives were synthesized and evaluated for their in vitro antimalarial activity against P. falciparum. Out of the 24 compounds synthesized six compounds have shown MIC of 1 microg/mL. These compounds are in vitro several folds more active than pyrimethamine.
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