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  • Title: [Hypoglycemia associated with oral sulfonylurea hypoglycaemic agents in an 11-year-old girl].
    Author: Ramos E, Baron S, Sentanac S, Touati G, Picherot G.
    Journal: Arch Pediatr; 2005 Jul; 12(7):1109-11. PubMed ID: 15925501.
    Abstract:
    UNLABELLED: In children more than 8 years old, hyperinsulinism is the most common cause of hypoglycemia. CASE REPORT: We report the case of an 11-year-old girl who presented recurrent hypoglycemia with endogenous hyperinsulinism (high insulin and C-peptide concentrations). The morphological investigations didn't find insulinoma. Finally the questioning identifies the voluntary intoxication with hypoglycemic agent. At a later date, the sulfonylurea dosage during an hypoglycaemic episode was positive. CONCLUSION: The sulfonylurea drugs can mimic an endogenous hyperinsulinism and mislead the diagnostic to an insulinoma suspicion and lead to a surgical exploration. A sulfonylurea dosage should be done before planning out surgery.
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