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  • Title: [Diagnosis, care, and therapeutic possibilities in intravascular B-cell lymphoma--a case report].
    Author: Takács I, Tordai L, Eros N, Mórocz I, Bozsó F, Károlyi Z, Radványi G, Matolcsy A.
    Journal: Orv Hetil; 2005 May 01; 146(18):843-8. PubMed ID: 15926630.
    Abstract:
    The cutaneous angiotropic lymphoma has a poor prognosis. The diagnosis and the treatment are usually late. The mortality rate is over 80% and the majority of patients die within a year because of the tumorous infiltration of parenchymal organs. The authors report here the medical history and follow up of a still living patient suffering from cutaneous angiotropic lymphoma which has been diagnosed sixty months ago. During the successful treatment course systemic treatment with psoralen ultraviolet A-rays, chlorambucil and cyclophosphamide-doxorubicin-vincristine-methylprednisolone chemotherapy was applied, and for the management of the last relapse, rituximab-cyclophosphamide-doxorubicin-vincristine-methylprednisolone polychemotherapy was used. On the basis of findings in this case a treatment using an anti-CD20 monoclonal antibody could be a promising therapeutic alternative in the management of angiotropic B-cell lymphoma which otherwise considered to be a rare entity.
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