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  • Title: New pregnane glycosides from Caralluma dalzielii.
    Author: De Leo M, De Tommasi N, Sanogo R, Autore G, Marzocco S, Pizza C, Morelli I, Braca A.
    Journal: Steroids; 2005 Aug; 70(9):573-85. PubMed ID: 15927219.
    Abstract:
    Twenty-seven new pregnane glycosides were isolated from the whole plant of Caralluma dalzielii, and their structures elucidated from extensive 2D NMR analysis as well as ESI-MS experiments. All isolated compounds were tested for their antiproliferative activity on J774.A1, HEK-293, and WEHI-164 cell lines. Moderate to high potency of cytotoxicities were found in almost all tested compounds, confirming the significant cytotoxic activity of pregnane glycosides.
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