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  • Title: Acute toxicity, uptake and clearance of diazinon by the European eel, Anguilla anguilla (L.).
    Author: Sancho E, Ferrando MD, Andreu E, Gamon M.
    Journal: J Environ Sci Health B; 1992 Apr; 27(2):209-21. PubMed ID: 1593096.
    Abstract:
    The toxicity, accumulation, and elimination of diazinon were investigated for the european eel, Anguilla anguilla. The 24, 48, 72 and 96-h median lethal concentrations (LC50) were 0.16, 0.11, 0.09 and 0.08 mg/L, respectively. Fish exposed to sublethal concentration (0.042 mg/L) accumulated diazinon in liver and muscle tissues. Bioconcentration factors (BCF) of diazinon were 1850 in liver, and 775 in muscle over the 96-h exposure period. Upon removal from diazinon containing water the contaminated fish rapidly eliminated diazinon. The excretion rate constants of this insecticide were 0.108 h-1 for liver and 0.016 h-1 for muscle. Diazinon half-lives were 16.6 and 33.2 hours for liver and muscle, respectively.
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