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  • Title: The short-term in situ model to evaluate the anticariogenic potential of ionomeric materials.
    Author: Tenuta LM, Ribeiro CC, Gonçalves NC, Del Bel Cury AA, Aires CP, Tengan C, Tagliaferro EP, Pecharki GD, Napimoga MH, Tabchoury CP, Cury JA.
    Journal: J Dent; 2005 Jul; 33(6):491-7. PubMed ID: 15935269.
    Abstract:
    OBJECTIVES: Aiming to contribute to the study of mechanisms involved in the anticariogenic properties of dental materials, this study assessed the suitability of a short-term in situ model to evaluate the anticariogenic potential of ionomeric materials. METHODS: The study used a 3-phase crossover, double blind design, and in each phase eight volunteers wore palatal appliances containing four enamel blocks restored with one of the following materials: composite resin (CR-Z250) (negative control), a conventional glass ionomer cement (GIC-Ketac-Fil) or a resin-modified GIC (RM-GIC-Vitremer). The restored blocks were covered with a "test plaque" of S. mutans, placed in palatal appliances and a cariogenic challenge was made during 1 min with 20% sucrose solution. After 45 min, test plaque was collected for fluoride (F) analysis. Enamel surface microhardness was previously determined at one side of the restoration and the percentage of surface microhardness change (%SMC) in relation to baseline (other side) was calculated. F concentration in enamel was also evaluated. RESULTS: Split-plot ANOVA showed a statistically lower %SMC on enamel around the ionomeric materials than around the CR (p<0.05). This result was supported by a statistically higher F concentration in test plaque (P<0.001) and in enamel (P<0.001) restored with the ionomeric materials when compared to the CR. CONCLUSIONS: The results suggest that the short-term in situ model tested is useful for studying the anticariogenic potential of dental materials that release fluoride.
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