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  • Title: Design and simulation of active biochip system.
    Author: Zhu W, Zhu W, Zhang W, Han F, Dong X, Yan X.
    Journal: Biomed Microdevices; 2005 Jun; 7(2):157-60. PubMed ID: 15940432.
    Abstract:
    To solve the problems existing in passive biochip systems, we designed a novel active biochip system. This system introduces negative pressure and controlling devices to adjust the antigen-antibody reaction on the nitrocellulose membrane. Computational simulation demonstrated that this system is a rapid, stable, robust and practical system that may enhance the efficiency of antigen-antibody reactions and improve the repeatability and accuracy of biochip analysis.
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