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Title: Solution- and solid-phase synthesis of radicicol (monorden) and pochonin C. Author: Barluenga S, Moulin E, Lopez P, Winssinger N. Journal: Chemistry; 2005 Aug 19; 11(17):4935-52. PubMed ID: 15940738. Abstract: A modular synthesis for pochonin C and radicicol is reported. The two natural products were prepared in seven and eight steps, respectively, from three readily available fragments. Alternative syntheses of these compounds were achieved using a combination of polymer-bound reagents and solid phase reactions. The conformation of the two natural products was studied and compared by using 2D NMR spectroscopy.[Abstract] [Full Text] [Related] [New Search]