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  • Title: Dosage compensation in flies: mechanism, models, mystery.
    Author: Straub T, Dahlsveen IK, Becker PB.
    Journal: FEBS Lett; 2005 Jun 13; 579(15):3258-63. PubMed ID: 15943970.
    Abstract:
    Dosage compensation involves fine-tuning of gene expression at the level of entire chromosomes. The principles that assure selective targeting of the male X chromosome in Drosophila and the mechanism by which transcription levels are adjusted in a twofold range are still mysterious. We discuss the prevalent models in the context of recent experimental observations.
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