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Title: Rituximab monotherapy for splenic marginal zone lymphoma. Author: Bennett M, Sharma K, Yegena S, Gavish I, Dave HP, Schechter GP. Journal: Haematologica; 2005 Jun; 90(6):856-8. PubMed ID: 15951303. Abstract: In this retrospective study, rituximab was found to be effective therapy in 10 of 11 patients with splenic marginal zone lymphoma, inducing prompt reduction in splenomegaly, improvement in blood counts in 9 patients and clearance of a pleural effusion in 1 patient. Median response duration was 21 months (range 4 to 37 months). Two patients who relapsed at 21 and 23 months responded to retreatment. Rituximab should be considered in patients who are poor candidates for splenectomy.[Abstract] [Full Text] [Related] [New Search]