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  • Title: In situ hybridization of PNA/DNA studied label-free by electrochemical impedance spectroscopy.
    Author: Liu J, Tian S, Nielsen PE, Knoll W.
    Journal: Chem Commun (Camb); 2005 Jun 21; (23):2969-71. PubMed ID: 15957042.
    Abstract:
    The in situ hybridization kinetics of label-free DNA on mixed monolayers of peptide nucleic acid (PNA) and 6-mercapto-1-hexanol (MCH) on Au electrodes was investigated by electrochemical impedance spectroscopy (EIS) and used to discriminate the fully complementary DNA from the single-base mismatched hybrids.
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