These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Stereoselective synthesis of the tetrahydropyran core of polycarvernoside A.
    Author: Barry CS, Bushby N, Harding JR, Willis CL.
    Journal: Org Lett; 2005 Jun 23; 7(13):2683-6. PubMed ID: 15957921.
    Abstract:
    [reaction: see text] A concise and stereoselective synthesis of the tetrasubstituted tetrahydropyran core of polycavernoside A was achieved in 55% overall yield from 3-benzyloxypropanal. A stereoselective allyl transfer reaction was used in the synthesis of enol ether 18 followed by a TFA-mediated cyclization to create the three new asymmetric centers in the tetrahydropyran with complete stereocontrol in a single-pot process.
    [Abstract] [Full Text] [Related] [New Search]