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  • Title: Increased mucin levels in submandibular saliva from mice following repeated isoproterenol treatment.
    Author: Denny PA, Hong SH, Klauser DK, Denny PC.
    Journal: Arch Oral Biol; 1992 Jan; 37(1):73-5. PubMed ID: 1596213.
    Abstract:
    Mucin decreases with age in the submandibular glands of mice and can be restored by chronic administration of isoproterenol. Mice were given repeated injections of isoproterenol to determine if the increase of mucin in the submandibular gland leads to elevated levels of mucin in the submandibular saliva. Mucin was significantly elevated in both the gland and the saliva after isoproterenol. Gland contents of mucin and the concentration of mucin in their salivas were positively correlated for both the isoproterenol (p = 0.01) and the control group (p less than 0.01).
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