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Title: Effects of calcium antagonists on the cocaine- and methamphetamine-induced conditioned place preference. Author: Suzuki T, Shiozaki Y, Masukawa Y, Misawa M. Journal: Arukoru Kenkyuto Yakubutsu Ison; 1992 Feb; 27(1):81-90. PubMed ID: 1596245. Abstract: The effects of calcium antagonists (nifedipine, flunaridine and diltiazem) on the cocaine- and methamphetamine-induced place preference were examined. Calcium antagonists alone induced neither place preference nor place aversion. Nifedipine markedly antagonized and flunarizine and diltiazem reduced the cocaine-induced place preference. The methamphetamine-induced place preference was reduced by nifedipine and diltiazem, but not by flunarizine. These results suggest the possibility that the cocaine-induced place preference is strongly influenced by dihydropyridine sensitive calcium channels, whereas the methamphetamine-induced place preference is not.[Abstract] [Full Text] [Related] [New Search]