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  • Title: First partial characterisation of small ruminant lentiviruses from Greece.
    Author: Angelopoulou K, Karanikolaou K, Papanastasopoulou M, Koumpati-Artopiou M, Vlemmas I, Papadopoulos O, Koptopoulos G.
    Journal: Vet Microbiol; 2005 Aug 10; 109(1-2):1-9. PubMed ID: 15964721.
    Abstract:
    Small ruminant lentivirus (SRLV) infections are widespread in Greece, but SRLVs have never been isolated and characterized. In this study, we present the sequence of a 574-nucleotide (191-amino acid) region of the gag gene of SRLV strains from four sheep and one goat from a single geographic area of Greece. All five sequences appeared to be closely related at both nucleotide (2.1-14.2% variation) and deduced amino acid (1.6-4.2% variation) level. Greek SRLV strains were closer to ovine prototypic strains (average divergence 16.8%) than to the caprine strain CAEV-Co (21% divergence). By amino acid composition, the Greek SRLVs were on the average more than twice as distant from CAEV-Co as from other ovine strains. Phylogenetic analysis suggested that Greek strains segregate into a unique group, separate from, but related to, other ovine prototype sequences.
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