These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Repopulation of cancer cells during therapy: an important cause of treatment failure.
    Author: Kim JJ, Tannock IF.
    Journal: Nat Rev Cancer; 2005 Jul; 5(7):516-25. PubMed ID: 15965493.
    Abstract:
    Radiotherapy and chemotherapy are given in multiple doses, which are spaced out to allow the recovery of normal tissues between treatments. However, surviving cancer cells also proliferate during the intervals between treatments and this process of repopulation is an important cause of treatment failure. Strategies developed to overcome repopulation have improved clinical outcomes, and now new strategies to inhibit repopulation are emerging in parallel with advances in the understanding of underlying biological mechanisms.
    [Abstract] [Full Text] [Related] [New Search]