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  • Title: Hox clusters as models for vertebrate genome evolution.
    Author: Hoegg S, Meyer A.
    Journal: Trends Genet; 2005 Aug; 21(8):421-4. PubMed ID: 15967537.
    Abstract:
    The surprising variation in the number of Hox clusters and the genomic architecture within vertebrate lineages, especially within the ray-finned fish, reflects a history of duplications and subsequent lineage-specific gene loss. Recent research on the evolution of conserved non-coding sequences (CNS) in Hox clusters promises to reveal interesting results for functional and phenotypic diversification.
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