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  • Title: MRI-T2 values in the differentiation of recurrence and fibrosis after radiation of nasopharyngeal carcinoma.
    Author: Gong QY, Zhu HY, Zheng GL, Wang Y, Yuan CM, Cheng L, Wu PH, Lu LX, Huang QL, Zhang XL.
    Journal: Chin Med J (Engl); 1992 Feb; 105(2):135-8. PubMed ID: 1597073.
    Abstract:
    The possibility of T2 values in the differentiation of local recurrence and irradiation fibrosis was studied prospectively in 36 patients with nasopharyngeal carcinoma (NPC) after radiotherapy. All the patients had a soft-tissue mass in the nasopharynx demonstrated by CT. Fourteen patients had tumor recurrence, 20 radiation fibrosis, 1 postradiation edema, and 1 inflammatory change. The control group consisted of 8 patients with untreated NPC. It was found that T2 was longer in patients with tumor than in patients with radiation fibrosis. We conclude that MRI may be used as a noninvasive method for differentiating radiation fibrosis from local recurrent NPC, but the prolonged T2 value of tumor is not specific and may be seen in radiation edema and infection.
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