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  • Title: Detecting curable disease following hepatectomy for colorectal metastases.
    Author: Metcalfe M, Mann C, Mullin E, Maddern G.
    Journal: ANZ J Surg; 2005 Jul; 75(7):524-7. PubMed ID: 15972037.
    Abstract:
    INTRODUCTION: Although resection may be curative for patients with hepatic colorectal metastases, recurrence occurs in the majority. Recurrence is occasionally amenable to repeated resection. The aim of the present study was to evaluate which modalities, at what intervals, detected potentially curable resection. METHODS: The records of patients undergoing hepatectomy for colorectal metastases over 10 years in one centre were retrospectively reviewed to determine when and how recurrence was diagnosed. Specific attention was paid to the detection of potentially curable disease. RESULTS: Of 41 recurrences, 22 occurred in the first year postoperatively, 21 of which were suitable for palliative treatment only. Ten of 19 recurrences occurring after 1 year underwent potentially curative intervention, 10 were diagnosed by computed tomography (CT). Carcinoembryonic antigen did not diagnose any curable recurrence. CONCLUSIONS: A follow-up protocol is proposed, based on annual CT.
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