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  • Title: [The value of intraoperative rapid biopsy study in diagnosis of breast cancer].
    Author: Hanzal E, Gitsch G, Joura E, Dadak C, Breitenecker G.
    Journal: Geburtshilfe Frauenheilkd; 1992 Mar; 52(3):161-4. PubMed ID: 1597276.
    Abstract:
    432 biopsies of mammary tumours performed between 1988 and 1990 were reviewed to evaluate the accuracy of rapid frozen section diagnosis. 15 (3.47%) had to be deferred to await subsequent permanent paraffin section. There were 4 (2.55%) false negative diagnoses. These cases consisted of small, nonpalpable and in-situ lesions. No false positive diagnosis was noted during the observation period. Sensitivity of frozen section histology was 97.45%, specificity 100% and efficiency 96.53%. Rapid frozen section diagnosis is a highly accurate and reliable tool which helps to avoid a consecutive operation in patients with breast cancer.
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