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  • Title: Detection, discrimination and integration of second-order orientation information in strabismic and anisometropic amblyopia.
    Author: Mansouri B, Allen HA, Hess RF.
    Journal: Vision Res; 2005 Aug; 45(18):2449-60. PubMed ID: 15979466.
    Abstract:
    To better understand the nature of the cortical deficit in amblyopia we undertook a systematic investigation of second-order processing in 8 amblyopic and 8 normal observers. We investigated local detection, discrimination and global integration. Our local stimulus consisted of a Gaussian patch of fractal noise multiplied by a 1-d sinusoidal modulator. Our global stimulus consisted of an array of such elements. We revealed second-order detection deficits for stimuli with equi-visible carriers. Orientation discrimination for an isolated second-order patch was comparable in normal and amblyopic eyes. We showed that pure integration of second-order patterns can be normal in amblyopia.
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