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  • Title: In vitro antibacterial activity of DX-619, a novel des-fluoro(6) quinolone.
    Author: Fujikawa K, Chiba M, Tanaka M, Sato K.
    Journal: Antimicrob Agents Chemother; 2005 Jul; 49(7):3040-5. PubMed ID: 15980395.
    Abstract:
    The in vitro activities of DX-619, des-fluoro(6) quinolone, against 1,208 clinical isolates were examined. DX-619 was particularly potent against staphylococci, including ciprofloxacin- and methicillin-resistant strains; the MIC at which 90% of the strains tested were inhibited was 0.5 microg/ml. In addition, DX-619 was also active against gram-negative bacteria.
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